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Anti-Phospho-ACLY-S455 antibody produced in rabbit
产品别名
Anti-Phospho-ACLY-S455 antibody produced in rabbit
ACLY
ACL
ATPCL
CLATP
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 119 120 91 |
| species reactivity | human, mouse, rat |
| concentration【浓度】 | 1.15 mg/ml |
| technique(s) | immunohistochemistry: 1:50-1:100 immunoprecipitation (IP): 1:50-1:100 western blot: 1:500-1:2000 |
| UniProt accession no.【UniProt登记号】 | P53396 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... ACLY(47) |
基本信息
| General description【一般描述】 | ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. |
| Immunogen【免疫原】 | A synthetic phosphorylated peptide around S455 of human ACLY (NP_001087.2). |
| Physical form【外形】 | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
产品说明
| Storage and Stability【储存及稳定性】 | Store at -20℃. Avoid freeze / thaw cycles. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
