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Anti-Phospho-ERBB4-Y1284 antibody produced in rabbit
产品别名
Anti-Phospho-ERBB4-Y1284 antibody produced in rabbit
ERBB4
ALS19
p180erbB4
HER4/ErbB4
HER4
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 143 145 146 |
species reactivity | mouse, human, rat |
concentration【浓度】 | 2.55 mg/ml |
technique(s) | western blot: 1:500-1:2000 |
UniProt accession no.【UniProt登记号】 | Q15303 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... ERBB4(2066) |
基本信息
General description【一般描述】 | This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. |
Immunogen【免疫原】 | A synthetic phosphorylated peptide around Y1284 of human ERBB4 (NP_005226.1). |
Physical form【外形】 | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
产品说明
Storage and Stability【储存及稳定性】 | Store at -20℃. Avoid freeze / thaw cycles. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |