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产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | liquid |
| species reactivity | human, mouse |
| concentration【浓度】 | 0.974 mg/mL |
| technique(s) | western blot: 1:500-1:2000 |
| UniProt accession no.【UniProt登记号】 | O43318 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... MAP3K7(6885) |
基本信息
| General description【一般描述】 | The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. |
| Immunogen【免疫原】 | A phospho specific peptide corresponding to residues surrounding T187 of human MAP3K7. |
| Physical form【外形】 | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
