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Anti-podocalyxin associated keratan sulfate, clone R-10G| MABD151 Antibody

产品编号:4112949
规格:clone R-10G, from mouse
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4112949100 μG5680
产品别名

Anti-podocalyxin associated keratan sulfate, clone R-10G| MABD151 Antibody

Podocalyxin, PC, PCLP-1

基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
Podocalyxin-like protein 1 is a sialomucin that is involved in the regulation of both cell adhesion and cell morphology through its interactions with several intracellular and at least one extracellular ligand. It is known to play an essential role in the formation and maintenance of podocyte foot processes, in cancer development and aggressiveness and as a marker of undifferentiatted embryonic stem cells. MABD151, a monoclonal antibody generated against human iPS cells, is a novel marker antibody recognizing a type of keratan sulfate lacking oversulfated structure on hiPS cells. MABD151 is a useful molecular probe for disclosing the roles of glycans on the surface of hiPS cells in the maintenance of self-renewal and pluripotency and also as a potent tool for the evaluation and standardization of hiPS cells with different tissue origins and different histories in regenerative medicine (Kawabe K et.al, (2013) Glycobiology. v23, 322–336.
Immunogen【免疫原】
Whole Human iPS cells (Tic cell line).
Application【应用】
Research Sub Category
Pluripotent & Early Differentiation
Research Category
Stem Cell Research
This Anti-podocalyxin associated keratan sulfate antibody, clone R-10G is validated for use in ICC & western blotting for the detection of podocalyxin associated keratan sulfate.
Evaluated by Western Blot in human brain lysate.
Western Blot Analysis: 1µg/mL of this antibody detected podocalyxin associated keratin sulphate in 10 µg of human brain lysate.

Evaluated by Immunocytochemistry in human ES cells.
Immunocytochemical Analysis: A 1:250 dilution of this antibody detected odocalyxin associated keratin sulphate in human ES cells.
Quality【质量】
Evaluated by Western Blot in human ES cell lysate.

Western Blot Analysis: 1µg/mL of this antibody detected podocalyxin associated keratin sulphate in 10 µg of human ES cell lysate.
Physical form【外形】
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified
Other Notes【其他说明】
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
产品性质
Quality Level【质量水平】
100
biological source【生物来源】
mouse
antibody form【抗体形式】
purified immunoglobulin
antibody product type
primary antibodies
clone【克隆】
R-10G, monoclonal
species reactivity
human
should not react with
mouse
technique(s)
immunocytochemistry: suitable
western blot: suitable
isotype【同位素/亚型】
IgG1, kappa
NCBI accession no.【NCBI登记号】
NP_001018121
UniProt accession no.【UniProt登记号】
O00592
shipped in【运输】
wet ice
Gene Information
human ... PODXL(5420)
产品说明
Target description【目标描述】
above 250kDa
Storage and Stability【储存及稳定性】
Stable for 1 year at 2-8°C from date of receipt.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
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