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Anti-PRDM12 Antibody
| 产品编号： | 4113101 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-PRDM12 Antibody
PR domain zinc finger protein 12, PR domain-containing protein 12, arg methyltransferase, arginine methyltransferase, PR domain family
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET-domain-containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET-domain family, and another 17 make up the PR domain family that is related to the SET domain family. The retinoblastoma protein-interacting zinc finger gene RIZ1 is a tumor suppressor gene and the founding member of the PR domain family. PRDM12 (PR domain zinc finger protein 12) also acts as a tumor suppressor and is linked to the pathogenesis of chronic myeloid leukemia. PRDM12 is also thought to play a role in transcriptional regulation. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human PRDM12. |
| Application【应用】 | Research Sub Category Histones Research Category Epigenetics & Nuclear Function Use Anti-PRDM12 Antibody (Rabbit Polyclonal Antibody) validated in WB, ICC to detect PRDM12 also known as PR domain zinc finger protein 12, arginine methyltransferase. Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected PRDM12 in NIH/3T3 and A431 cells. |
| Quality【质量】 | Evaluated by Western Blot in human liver tissue lysate. Western Blot Analysis: 3 μg/mL of this antibody detected PRDM12 on 10 µg of human liver tissue lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Affinity purified |
| Analysis Note【分析说明】 | Control Human liver tissue lysate. |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human, mouse |
| technique(s) | immunocytochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_067632 |
| UniProt accession no.【UniProt登记号】 | Q9H4Q4 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... PRDM12(59335) |
产品说明
| Target description【目标描述】 | ~37 kDa observed |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
