广州伟伯科技有限公司
您的位置:首页 > 产品中心 > Anti-Pst1 antibody produced in rabbit
产品搜索:

Anti-Pst1 antibody produced in rabbit

产品编号:4113262
规格:affinity isolated antibody
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4113262100 μG4800
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
liquid
species reactivity
yeast
concentration【浓度】
1 mg/mL
technique(s)
ELISA: suitable
isotype【同位素/亚型】
IgG
UniProt accession no.【UniProt登记号】
Q12355
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
Saccharomyces cerevisiae ... PST1(851625)
基本信息
General description【一般描述】
Pst1 Antibody: Protoplast secreted protein 1 (Pst1) is an anchored plasma membrane protein. Pst1 was previously identified as a protein secreted by yeast regenerating protoplasts, which suggests a role in cell wall construction. Pst1 is a protein with 444 amino acids and is attached to yeast cell wall via a glycosylphosphatidylinisotol (GPI) anchor. Pst1 contains 15 potential N-linked glycosylation sites and is heavily glycosylated. It migrates at approximately 200 kDa on SDS-PAGE when produced in wild type S. cerevisiae. Our Pst1 protein (Catalog No. 95-151) was expressed in a genetically manipulated triple-mutant (TM) S. cerevisiae stain (Δoch1 Δmnn1 Δmnn4), which results in the production of sole Man8GlcNAc2 carbohydrate structures and Pst1 migration at approximately 100 kDa. When produced in the TM yeast, Pst1 can be recognized by several glycan-specific HIV-1 broadly neutralizing antibodies, including 2G12 and recently identified PGT antibodies. Among several heavily N-glycosylated TM yeast glycoproteins, Pst1 shows higher affinity for 2G12 and efficiently inhibits gp120 interactions with 2G12 and DC-SIGN, and it also blocks 2G12-mediated neutralization of HIV-1 pseudoviruses.
Immunogen【免疫原】
Pst1 antibody was raised against a synthetic peptide from the amino terminus of yeast Pst1.The immunogen is located within amino acids 80 - 130 of Pst1.
Application【应用】
Pst1 antibody can be used for detection of Pst1 by Western blot and ELISA at 1 μg/mL.
Physical form【外形】
Supplied in PBS containing 0.02% sodium azide.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
nwg
广州伟伯科技有限公司 版权所有 CopyRight ©2006-2024, All Rights Reserved
工信部备案号:粤ICP备08114744号   Page Run Time: 0.6309