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产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody product type | primary antibodies |
clone【克隆】 | monoclonal |
form【形式】 | liquid |
species reactivity | human |
concentration【浓度】 | 0.4 mg/mL |
technique(s) | immunohistochemistry: 1:50-1:200 western blot: 1:500-1:2000 |
UniProt accession no.【UniProt登记号】 | Q06587 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... RING1(6015) |
基本信息
General description【一般描述】 | This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4. [provided by RefSeq, Jul 2008] |
Immunogen【免疫原】 | A synthesized peptide derived from human RING1A A |
Physical form【外形】 | Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |