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Anti-SFRP2 Antibody, clone 80.8.6, azide free
产品别名
Anti-SFRP2 Antibody, clone 80.8.6, azide free
Secreted frizzled-related protein 2, FRP-2, sFRP-2, Secreted apoptosis-related protein 1, SARP-1
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Secreted frizzled-related proteins (SFRPs) may play a critical role in carcinogenesis by inhibiting the Wnt/beta-catenin signaling pathway. Secreted frizzled-related protein 2 (SFRP2) may be useful to further investigate mammary tumorigenesis as its expression increases with tumor progression in canine mammary gland tumors. SFRP2 in mouse embryos has been found to cause severe shortening of the thoracic region. Studies have shown that this protein is the essential stem cell paracrine factor that is thought to regulate myocardial survival and repair damage in the aftermath of an ischemic injury. |
| Immunogen【免疫原】 | Epitope: NTR domain Linear peptide corresponding to the NTR domain of human SFRP2. |
| Application【应用】 | Inhibition Assay Analysis: Anti-SFRP2, clone 80.8.6 inhibits tube formation and cell migration in vitro on SVR angiosarcoma cells, inhibits angiosarcoma and breast cancer growth in vivo, and increases nuclear NFATc3 levels. Anti-SFRP2 Antibody, clone 80.8.6, azide free is an antibody against SFRP2 for use in IHC & inhibition. |
| Quality【质量】 | Evaluated by Immunohistochemistry in human prostate and human breast cancer tissue. Imunnohistochemistry Analysis: A 1:500 dilution of this antibody detected SFRP2 in human prostate and human breast cancer tissue. |
| Physical form【外形】 | Protein G Purified Format: Purified |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | 80.8.6, monoclonal |
| species reactivity | human |
| technique(s) | immunohistochemistry: suitable inhibition assay: suitable |
| isotype【同位素/亚型】 | IgG2aκ |
| NCBI accession no.【NCBI登记号】 | NP_003004 |
| UniProt accession no.【UniProt登记号】 | Q96HF1 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... SFRP2(6423) |
产品说明
| Target description【目标描述】 | 33 kDa calculated |
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
