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Anti-SLC5A3 Antibody
| 产品编号： | 4114396 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-SLC5A3 Antibody
Sodium/myo-inositol cotransporter, Na(+)/myo-inositol cotransporter, Sodium/myo-inositol transporter 1, SMIT1, Solute carrier family 5 member 3
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | SLC5A3, also known as Sodium/myo-inositol cotransporter, Na (+)/myo-inositol cotransporter, Sodium/myo-inositol transporter 1 (SMT1), or Solute carrier family 5 member 3, and encoded by the gene SLC5A3, is an important intracellular transporter and signaling mediator that mediates the intracellular accumulation of myo-inositol. The compound myo-inositol is important for cell signaling both in the cytoplasm and in intracellular organelles. It is required in the plasma membrane and in the cytoplasm for maintaining the synthesis of the second messengers such as Inositol trisphosphate (IP3) and diacylglycerol (DAG) from phosphatidylinositol bisphosphate (PIP2). In organelles myo-inositol is a precursor for the synthesis of complex signaling phospholipids and inositolphosphates from IP3 and PIP2 as well. Moreover, SLC5A3 is upregulated by osmotic shock and downregulated by energy depletion and serves as a molecular sensor of cellular stress. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human SLC5A3. |
| Application【应用】 | Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected SLC5A3 in human prostate tissues. Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected SLC5A3 in human placenta tissues. Detect SLC5A3 using this Anti-SLC5A3 Antibody validated for use in western blotting & IHC (Paraffin). |
| Quality【质量】 | Evaluated by Western Blotting in HUVEC cell lysate. Western Blotting Analysis: 1 μg/mL of this antibody detected SLC5A3 in 10 μg of HUVEC cell lysate. |
| Other Notes【其他说明】 | Affinity purified |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human |
| technique(s) | immunohistochemistry: suitable (paraffin) western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_008864 |
| UniProt accession no.【UniProt登记号】 | P53794 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... SLC5A3(6526) |
产品说明
| Target description【目标描述】 | ~79 kDa observed |
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
