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Anti-STMN2 Antibody, clone L5/1
产品别名
Anti-STMN2 Antibody, clone L5/1
Stathmin-2, Superior cervical ganglion-10 protein, Protein SCG10
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Stathmin-like 2 (STMN2) protein is a phospho-protein and functions in microtubule dynamics and signal transduction. Studies show STMN2 plays a regulatory role in neuronal growth and thought to be involved in osteogenesis. Reduced levels, i.e. reduction in expression, have been associated with Down′s syndrome and Alzheimer′s disease. Data also suggests that STMN2 may play a role in modulating membrane interaction with the cytoskeleton during neurite outgrowth. |
| Immunogen【免疫原】 | Linear peptide corresponding to the C-terminus of rat STMN2. Epitope: C-terminus |
| Application【应用】 | Western Blotting Analysis: 0.5 µg/mL from a representative lot detected STMN2 in 10 µg of rat fetal brain (E16) tissue lysate. Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected STMN2 in rat hippocampus tissue. Immunocytochemistry Analysis: A representative lot detected STMN2 in cultured hippocampal neurons (Prof. J. Trimmer, University of Califnornia, Davis.). Detect STMN using this mouse monoclonal antibody, Anti-STMN2 Antibody, clone L5/1 validated for use in western blotting, IHC & ICC. Research Category Neuroscience Research Sub Category Developmental Signaling |
| Quality【质量】 | Evaluated by Western Blotting in SH-SY-5Y cell lysate. Western Blotting Analysis: 0.5 µg/mL of this antibody detected STMN2 in 10 µg of SH-SY-5Y cell lysate. |
| Physical form【外形】 | Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Format: Purified Protein G Purified |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | L5/1, monoclonal |
| species reactivity | human, rat |
| species reactivity (predicted by homology) | mouse (based on 100% sequence homology) |
| technique(s) | immunocytochemistry: suitable immunohistochemistry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG2bκ |
| NCBI accession no.【NCBI登记号】 | NP_445892 |
| UniProt accession no.【UniProt登记号】 | P21818 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~21 kDa observed |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
