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Anti-Tensin-3 Antibody
| 产品编号： | 4115115 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Tensin-3 Antibody
Tensin-3, Tensin-like SH2 domain-containing protein 1, Tumor endothelial marker 6
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Tensin-3 is a member of the Tensin family of proteins that serve as a connection between the cytoskeleton and extracellular matrix. Because of this link, Tensin’s are commonly thought to regulate signaling for the shape of the cell and motility. Tensin-3 localizes in the cell cytoplasm and has been shown to be significantly decreased in many different human cancer cell lines. Higher expression levels of Tensin-3 were also found to be associated with longer survival. Tensin-3 has also been found to be highly expressed in functioning thyroid follicular adenomas while expression is significantly lower in non-functioning thyroid follicular adenomas, which seems to imply that Tensin-3 has an important role in basic thyroid function. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human Tensin-3. |
| Application【应用】 | Research Category Cell Structure Research Sub Category ECM Proteins Cytoskeleton Anti-Tensin-3 Antibody detects level of Tensin-3 & has been published & validated for use in WB & IC. Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected Tensin-3 in A431 cells. |
| Quality【质量】 | Evaluated by Western Blot in human kidney tissue lysate. Western Blot Analysis: 1 µg/mL of this antibody detected Tensin-3 in 10 µg of human kidney tissue lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Affinity purified |
| Analysis Note【分析说明】 | Control Human kidney tissue lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human |
| technique(s) | immunocytochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_073585 |
| UniProt accession no.【UniProt登记号】 | Q68CZ2 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... TNS3(64759) |
产品说明
| Target description【目标描述】 | ~180 kDa observed. The calculated molecular weight is 155 kDa, however Tensin-3 has been shown as a ~180 kDa band in western blots (Cui, Y., et al. (2004). Molecular Cancer Research. 2:225–232). An uncharacterized band appears at ~22 kDa in some lysates. |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
