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产品别名
Anti-TNK1 Antibody
Non-receptor tyrosine-protein kinase TNK1, CD38 negative kinase 1
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | TNK1 (thirty-eight-negative kinase 1) is a non-receptor tyrosine kinase that is widely used in fetal development signaling and more narrowly used in adult tissues and lymphohematopoietic system cells. TNK1 seems to have regulatory ability on whether TNFalpha activates NF-kappaB or apoptosis. TNK1 can also inhibit Ras function and tumor growth. Mice with a TNK1 deficiency often show unprompted tumor growth, including lymphomas and carcinomas. TNK1 downregulation has also been shown in a large number of humans with diffuse large B-cell lymphoma. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human TNK1. |
| Application【应用】 | Detect TNK1 using this Anti-TNK1 Antibody validated for use in WB. |
| Quality【质量】 | Evaluated by Western Blot in HeLa cell lysate. Western Blot Analysis: 0.5 µg/mL of this antibody detected TNK1 on 10 µg of HeLa cell lysate. |
| Physical form【外形】 | Protein A Format: Purified |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| species reactivity | human |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_003976 |
| UniProt accession no.【UniProt登记号】 | Q13470 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... TNK1(8711) |
产品说明
| Target description【目标描述】 | ~72 kDa observed |
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
