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Atorvastatin Calcium Salt Trihydrate
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4116559 | 10 MG | 1150 | |||
4116559 | 50 MG | 3400 |
产品别名
344423-98-9
Atorvastatin Calcium Salt Trihydrate
[R-(R*, R*)]-2-(4-Fluorophenyl)-β, δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1Hpyrrole-1-heptanoic acid, calcium salt (2:1) trihydrate
(betaR,deltaR)-2-(p-Fluorophenyl)-beta,delta-dihydroxy-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrole-1-heptanoate, calcium salt (2:1) trihyddrate
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C66H68F2N4O10 · Ca · 3H2O |
Molecular weight | 1209.39 |
Biochem/physiol Actions【生化/生理作用】 | Atorvastatin calcium salt trihydrate is a specific inhibitor of β-Hydroxy β-methylglutaryl-CoA (HMG-CoA) reductase. HMG-CoA reductase is the enzyme that catalyzes the conversion of HMG-CoA to mevalonate, an early step in cholesterol biosynthesis. Atorvastatin is used in the treatment of hypercholesterolemia. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
optical activity【旋光性】 | [α]/D -9.0 to -5.0°, c = 0.5 in DMSO |
storage condition【储存条件】 | protect from light |
color【颜色】 | white to beige |
solubility【溶解性】 | DMSO: 2 mg/mL, clear |
storage temp.【储存温度】 | room temp |
SMILES string | O=C(C1=C(C(C)C)N(CC[C@@H](O)C[C@@H](O)CC([O-])=O)C(C2=CC=C(C=C2)F)=C1C3=CC=CC=C3)NC4=CC=CC=C4.[Ca+2].[3.0H2O] |
安全信息
Pictograms【象形图】 | GHS08 |
Signal word【警示用语:】 | Danger |
Hazard Statements | H351 - H360D |
Precautionary Statements | P201 - P202 - P280 - P308 + P313 - P405 - P501 |
Hazard Classifications【危险分类】 | Carc. 2 - Repr. 1B |
Storage Class Code【储存分类代码】 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
WGK | WGK 3 |