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BRCA1 human

产品编号:4116918
规格:recombinant, expressed in insect cells, ≥70% (SDS-PAGE)
包装规格:2 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
41169182 μG7230
产品别名

BRCA1 human

PNCA4

BRCC1

IRIS

BROVCA1

RNF53

BRCAI

PSCP

基本信息
NACRES
NA.26
Biochem/physiol Actions【生化/生理作用】
The human BRCA1, the product of breast and ovarian cancer gene 1, is a hyperphosphorylated protein functioning as a tumor suppressor involved in both transcription regulation and DNA repair. BRCA1 associates with RAD51 and has shown to be required for transcription-coupled repair of DNA damage as well as for the repair of chromosomal double-strand breaks. Association with a human SWI/SNF-related complex has recently suggested a potential role of BRCA1 in linking chromatin remodeling to breast cancer.
Physical form【外形】
Clear and colorless frozen liquid solution
Preparation Note【制备说明】
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.
产品性质
biological source【生物来源】
human
recombinant【重组】
expressed in insect cells
Assay【测定】
≥70% (SDS-PAGE)
form【形式】
frozen liquid
mol wt【分子量】
~209 kDa
packaging【包装】
pkg of 20 μg
storage condition【储存条件】
avoid repeated freeze/thaw cycles
concentration【浓度】
350  μg/mL
color【颜色】
clear
colorless
NCBI accession no.【NCBI登记号】
NM_007296
UniProt accession no.【UniProt登记号】
P38398
shipped in【运输】
dry ice
storage temp.【储存温度】
−70℃
Gene Information
human ... BRCA1(672)
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 1
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