CD160/BY55 human

NA.32

CD160 antigen also known as natural killer cell receptor BY55, is a 27 kDa glycoprotein, contains 1 Ig-like V-type (immunoglobulin-like) domain. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and non-classical MHC class I molecules. When expressed on vascular endothelial cells, CD160 propagates anti-angiogenic signals and promotes apoptosis.

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.

Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8℃ for up to 1 month. For extended storage, it is recommended to store at -20℃.

human

expressed in HEK 293 cells

6-His tagged (C-terminus)

≥95% (SDS-PAGE)

lyophilized

calculated mol wt 15.6 kDa
observed mol wt 22-28 kDa (DTT-reduced. Protein migrates due to glycosylation. Ile 27 is the predicted N-terminus.)

pkg of 10 μg

<1 EU/μg endotoxin (LAL test)

O95971

wet ice

−20℃

human ... CD160(11126)

11 - Combustible Solids

WGK 3