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Cefiderocol
产品别名
1225208-94-5
Cefiderocol
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C30H34ClN7O10S2 |
| Molecular weight | 752.21 |
| MDL number | MFCD30533432 |
| General description【一般描述】 | Cefiderocol is a novel injectable siderophore cephalosporin, which was formerly known as S-649266.(1)(3) It has a catechol-type siderophore and cephalosporin core and side chains.(1) Cefiderocol has structural similarity with both ceftazidime and cefepime, besides the chlorocatechol group on the end of the C-3 chain.(2) |
| Biochem/physiol Actions【生化/生理作用】 | Cefiderocol has strong antimicrobial properties especially against a wide spectrum of Gram-negative pathogens.(1)(3) Due to its siderophore core, it is also a natural iron-chelator, which adds to its antibacterial activities.(1) |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (HPLC) |
| antibiotic activity spectrum【抗生素抗菌谱】 | Gram-negative bacteria |
| Mode of action【作用机制】 | protein synthesis | inhibits |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | NC1=NC(/C(C(N[C@@H]2C(N3[C@@H]2SCC(C[N+]4(CCCC4)CCNC(C5=CC=C(O)C(O)=C5Cl)=O)=C3C([O-])=O)=O)=O)=N/OC(C(O)=O)(C)C)=CS1 |
