DUSP22, active, GST tagged human

NA.32

Dual specificity phosphatases (DUSP) family, which can dephosphorylate both phosphoserine/threonine and phosphotyrosine residues, comprise of two subgroups: "typical" DUSP (include 11 MKPs that dephosphorylate the mitogen-activated protein kinases Erk, Jnk, and p38 at their dually phosphorylated TXY activation loop motif) and "atypical" DUSP (include 8 enzymes that lack specific MAP kinase-targeting motifs and tend to be much smaller proteins, which are less than 250 amino acid residues). DUSP22, also called JKAP, JSP1 and MKPX plays a role in various inflammatory and proliferative disorders associated with dysfunctional Jnk signaling.

Supplied in 20mM MOPS, pH 7.5, 50mM NaCl, 10mM glutathione, 0.25mM DTT, 0.1mM PMSF, 30% glycerol.

after opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles

expressed in E. coli

≥70% (SDS-PAGE)

buffered aqueous glycerol solution

510-690 nmol/min·mg

~43 kDa

NM_020185

dry ice

−70℃

human ... DUSP22(56940)

10 - Combustible liquids

WGK 1