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Etravirine
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4118562 | 10 MG | 1068 | |||
4118562 | 50 MG | 3740 |
产品别名
269055-15-4
Etravirine
4-((6-Amino-5-bromo-2-((4-cyanophenyl)amino)pyrimidin-4-yl)oxy)-3,5-dimethylbenzonitrile
4-[[4-amino-5-bromo-6-(4-cyano-2,6-dimethylphenyloxy)-2-pyrimidinyl]amino]benzonitrile
4-[[6-Amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile
TMC125
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C20H15BrN6O |
Molecular weight | 435.28 |
MDL number | MFCD09837879 |
Biochem/physiol Actions【生化/生理作用】 | Etravirine is a second-generation Nonnucleoside reverse transcriptase inhibitor (NNRTI) anti-retroviral. It is active against HIV with mutations that confer resistance to the two most commonly prescribed first-generation NNRTIs, mutation K103N for efavirenz and Y181C for nevirapine. |
产品性质
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
color【颜色】 | white to beige |
solubility【溶解性】 | DMSO: 2 mg/mL, clear |
storage temp.【储存温度】 | 2-8℃ |
InChI | 1S/C20H15BrN6O/c1-11-7-14(10-23)8-12(2)17(11)28-19-16(21)18(24)26-20(27-19)25-15-5-3-13(9-22)4-6-15/h3-8H,1-2H3,(H3,24,25,26,27) |
InChI key | PYGWGZALEOIKDF-UHFFFAOYSA-N |
安全信息
Pictograms【象形图】 | GHS09 |
Signal word【警示用语:】 | Warning |
Hazard Statements | H410 |
Precautionary Statements | P273 |
Hazard Classifications【危险分类】 | Aquatic Acute 1 - Aquatic Chronic 1 |
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |