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FOS, GST tagged human

产品编号:4118796
规格:recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
CAS NO:1849687-41-7
包装规格:50 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
411879650 μG6360
产品别名

1849687-41-7

FOS, GST tagged human

C-FOS

基本信息
NACRES
NA.32
General description【一般描述】
FOS is a member of the FOS gene family that consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. FOS gene encodes a leucine zipper protein that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. FOS overexpression leads to decreased phosphorylation and dimerization of STAT1, which in turn downregulates p21 gene expression. This regulatory pathway may enhance the proliferation of lymphocytes in rheumatoid arthritis patients.
Physical form【外形】
Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Preparation Note【制备说明】
after opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles
产品性质
biological source【生物来源】
human
recombinant【重组】
expressed in baculovirus infected Sf9 cells
Assay【测定】
≥70% (SDS-PAGE)
form【形式】
buffered aqueous glycerol solution
mol wt【分子量】
~78 kDa
NCBI accession no.【NCBI登记号】
NM_005252
application(s)
cell analysis
shipped in【运输】
dry ice
storage temp.【储存温度】
−70℃
Gene Information
human ... FOS(2353)
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 1
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