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HDAC/SIRT Substrate 1, fluorogenic
产品别名
HDAC/SIRT Substrate 1, fluorogenic
histone deacetylase
HDAC
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | A fluorogenic, acetylated peptide substrate for HDAC′s. Based on residues 379-382 of p53, Arg-His-Lys-Lys, Ac, a site of regulatory acetylation by the p300 and CBP acetyltransferases, lysines 381, 382, 1-3, it is a suitable substrate for HDAC2, HDAC3, and HDAC6 tested so far. |
| Application【应用】 | Study enzyme kinetics, and screen small molecule inhibitors for drug discovery and HTS applications. |
| Physical form【外形】 | Supplied as a 5 mM solution in DMSO. |
产品性质
| Assay【测定】 | ≥90% (HPLC) |
| form【形式】 | aqueous solution |
| packaging【包装】 | pkg of 500 nmol |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 3 |
| Flash Point(F)【闪点(F)】 | 188.6 °F - closed cup |
| Flash Point(C)【闪点(C)】 | 87 ℃ - closed cup |
