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Hop human
| 产品编号： | 4119215 |
| 规格： | recombinant, expressed in E. coli, ≥99% (SDS-PAGE) |
| 包装规格： | 25 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Hop human
STI1
Renal carcinoma antigen NY-REN-11
Stress-induced-phosphoprotein 1
Hsc70/Hsp90-organizing protein
Transformation-sensitive protein IEF SSP 3521
基本信息
| NACRES | NA.32 |
| Biochem/physiol Actions【生化/生理作用】 | STIP1 (stress induced phosphoprotein 1) is an adaptor protein, which helps HSP70 (heat shock protein) and HSP90 in protein folding. It interacts with HSP90 and substrate-bound HSP70 and thereby, helps in transferring of proteins from HSP70 to HSP90. It also induces ATPase activity of HSP70 and suppresses that of HSP90. STIP1 serves as a potential biomarker for ovarian carcinoma. In psoriatic epidermis, it might be associated with hyperproliferation and abnormal differentiation via ERK (extracellular signal-regulated kinase) and c-Jun N-terminal kinase (JNK). |
| Physical form【外形】 | 4.5 mg/ml in 40 mM Hepes, pH 7.5. |
| Reconstitution【重悬】 | Centrifuge the vial prior to opening. Avoid freeze-thaw cycles. |
产品性质
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in E. coli |
| Assay【测定】 | ≥99% (SDS-PAGE) |
| form【形式】 | liquid |
| packaging【包装】 | pkg of 25 μg |
| storage condition【储存条件】 | avoid repeated freeze/thaw cycles |
| impurities【杂质】 | <1 EU/μg (LAL test) |
| NCBI accession no.【NCBI登记号】 | P31948 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
| Gene Information | human ... STIP1(10963) |
