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Human MMP-1 ELISA Kit
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | The Human MMP-1 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human MMP-1 cell lysate and tissue lysate. |
| Immunogen【免疫原】 | Recombinant Human MMP1 |
| Application【应用】 | 请参考Protocol了解详情。 |
| Biochem/physiol Actions【生化/生理作用】 | Matrix metalloproteinases (MMPs) enzymes play a central role in the maintenance and remodeling of the extracellular matrix. Elevated expression of their activity, caused either by up-regulation of their expression or down-regulation of their cognate inhibitors, has been implicated in various degenerative disorders, including arthritis, cardiovascular diseases, skeletal growth-plate disorders, and cancer metastasis. MMP-1 is a secreted collagenase with specificity toward Type I, II, III, VII, and X collagens, aggrecan, serpins, and α2-macroglobulin. It is overexpressed in lumbar intervertebral disc degeneration (IDD). It might also be associated with rheumatoid arthritis and osteoarthritis. MMP-1 is linked with juvenile idiopathic arthritis. Genetic variations in MMP-1 can affect the susceptibility and severity of this disease. MMP-1 might facilitate fibrous plaque disruption via degradation of interstitial collagens and thinning of the fibrous cap. |
| Other Notes【其他说明】 | A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number. |
| Components【组分】 | 组份可单独销售 RABDIL6 ELISA 5X Sample Diluent Buffer (Item D2) RABELADE ELISA 5X Assay/Sample Diluent Buffer E (Item E2) RABLYSIS1 2X Cell Lysis Buffer (Item J) RABSTOP3 ELISA Stop Solution (Item I) RABTMB3 ELISA Colorimetric TMB Reagent (HRP Substrate, Item H) RABWASH4 20X Wash Buffer (Item B) |
产品性质
| species reactivity | human |
| packaging【包装】 | kit of 96 wells (12 strips x 8 wells) |
| technique(s) | ELISA: suitable capture ELISA: suitable |
| input | sample type cell lysate sample type tissue lysate |
| assay range | inter-assay cv: <12% intra-assay cv: <10% sensitivity: 8 pg/mL standard curve range: 24.69-18000 pg/mL |
| Detection Method | colorimetric |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... MMP1(4312) |
安全信息
| Pictograms【象形图】 | GHS05 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H290 |
| Precautionary Statements | P234 - P390 |
| Hazard Classifications【危险分类】 | Met. Corr. 1 |
| Storage Class Code【储存分类代码】 | 8A - Combustible, corrosive hazardous materials |
| WGK | WGK 3 |
