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IL-1 Receptor Type I (human): FC (human)
| 产品编号： | 4119467 |
| 规格： | recombinant, expressed in HEK 293 cells, >95% (SDS-PAGE) |
| 包装规格： | 50 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
IL-1 Receptor Type I (human): FC (human)
Serpin F1
Interleukin-1 receptor alpha
RI
Interleukin-1 receptor type I
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | IL-1RI is the receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappaB. Signaling involves formation of a ternary complex containing IL1RAP, leading the activation of TOLLIP, MYD88, and IRAK1 or IRAK2. |
| Physical form【外形】 | Lyophilized from PBS. |
| Reconstitution【重悬】 | Reconstitute with 50 μL deionized water. |
| Other Notes【其他说明】 | Human IL-1RI (interleukin-1 receptor type I) (aa 21-336) is fused at the C-terminus to the Fc portion of human IgG1. |
产品性质
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in HEK 293 cells |
| Assay【测定】 | >95% (SDS-PAGE) |
| form【形式】 | lyophilized |
| mol wt【分子量】 | ~80 kDa by SDS-PAGE |
| packaging【包装】 | pkg of 50 μg |
| storage condition【储存条件】 | avoid repeated freeze/thaw cycles |
| impurities【杂质】 | <0.1 EU/μg endotoxin, tested |
| color【颜色】 | white |
| UniProt accession no.【UniProt登记号】 | P14778 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... IL1R1(3554) |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
