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Human Recombinant Animal Free
Human Recombinant Animal Free
IL-10,
Human Recombinant Animal Free
产品别名
IL-10,
Human Recombinant Animal Free
Interleukin-10, IL10
基本信息
eCl@ss | 32160405 |
NACRES | NA.75 |
General description【一般描述】 | IL-10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes. IL-10 inhibits the expression of proinflammatory cytokines such as IL-1 and TNF-α. Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions. Human IL-10 active on murine cells, but murine IL-10 is inactive on human cells. Recombinant human IL-10 is an 18.6 kDa protein of 161 amino acid residues. Product Source: Protein is expressed in E.coli. The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided. |
Application【应用】 | Research Category Stem Cell Research Research Sub Category Growth Factors & Receptors |
Quality【质量】 | The ED50 was determined by the dosedependent co-stimulation (with human IL-4) of MC/9 cells. The expected ED50 is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 10^5 units/mg. |
Physical form【外形】 | Product is presented in 20 mM Sodium Phosphate, pH 7.2. and is filtered through a 0.2 micron filter before lyophilization. |
产品性质
impurities【杂质】 | <0.1 μg/mg protein endotoxin (<1 EU/μg) |
Quality Level【质量水平】 | 100 |
UniProt accession no.【UniProt登记号】 | P15248 |
shipped in【运输】 | dry ice |
产品说明
Storage and Stability【储存及稳定性】 | Store at -20°C for up to 4 months from date of receipt Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein and store in working aliquots at -20°C. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 1 |