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KLRB1 human
产品编号: | 4119709 |
规格: | recombinant, expressed in E. coli, ≥85% (SDS-PAGE) |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
KLRB1 human
CLEC5B
NKRP1A
NKR-P1
NKR
CD161
NKR-P1A
Killer cell lectin-like receptor subfamily B member 1
hNKR-P1A
基本信息
NACRES | NA.32 |
General description【一般描述】 | Killer cell lectin-like receptor subfamily B member 1, also known as KLRB1, plays an inhibitory role on natural killer (NK) cells cytotoxicity. Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. Recombinant human KLRB1 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
Physical form【外形】 | 1 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol. |
产品性质
biological source【生物来源】 | human |
recombinant【重组】 | expressed in E. coli |
Assay【测定】 | ≥85% (SDS-PAGE) |
form【形式】 | liquid |
mol wt【分子量】 | 21 kDa (183 aa, 67-225 aa + His Tag) |
packaging【包装】 | pkg of 100 μg |
concentration【浓度】 | 1 mg/mL |
UniProt accession no.【UniProt登记号】 | Q12918 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −70℃ |
Gene Information | human ... KLRB1(3820) |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |