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Lalistat 2
产品别名
1234569-09-5
Lalistat 2
1-Piperidinecarboxylic acid 4-(1-piperidinyl)-1,2,5-thiadiazol-3-yl ester
Lalistat-2
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C13H20N4O2S |
Molecular weight | 296.39 |
MDL number | MFCD31544494 |
NACRES | NA.77 |
Application【应用】 | Lalistat 2 has been used as a lysosomal acid lipase (LAL) inhibitor to study its effects on hypoxia-inducible factor (HIF) in mice. It has also been used as a LAL inhibitor to study LAL activity on dried blood spot cards. |
Biochem/physiol Actions【生化/生理作用】 | Lalistat-2 is a potent and specific competitive inhibitor of the lysosomal acid lipase (LAL/Lipa). Lalistat-2 affects lipid droplets morphology and localization. |
产品性质
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
color【颜色】 | white to beige |
solubility【溶解性】 | DMSO: 2 mg/mL, clear |
storage temp.【储存温度】 | 2-8℃ |
SMILES string | O=C(N1CCCCC1)OC2=NSN=C2N3CCCCC3 |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |