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LATS2 (480-1088),活性,GST 标记 人
LATS2 (480-1088), active, GST tagged human
产品编号: | 4119785 |
规格: | PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution |
CAS NO: | 1843197-91-0 |
包装规格: | 10 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
1843197-91-0
LATS2 (480-1088),活性,GST 标记 人
LATS2 (480-1088), active, GST tagged human
基本信息
NACRES | NA.32 |
General description【一般描述】 | LATS2 is a serine/threonine protein kinase belonging to the LATS tumor suppressor family. LATS2 interacts with a negative regulator of p53 and function in a positive feedback loop with p53 that responds to cytoskeleton damage and this interaction provokes centrosome/mitotic apparatus dysfunction. LATS2 plays an essential role in the maintenance of mitotic fidelity and genomic integrity. |
Physical form【外形】 | Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Preparation Note【制备说明】 | after opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles |
Legal Information【法律信息】 | PRECISIO is a registered trademark of sigma-aldrich Co. LLC |
产品性质
biological source【生物来源】 | human |
recombinant【重组】 | expressed in baculovirus infected Sf9 cells |
product line【产品线】 | PRECISIO® Kinase |
Assay【测定】 | ≥70% (SDS-PAGE) |
form【形式】 | buffered aqueous glycerol solution |
Specific Activity | 9.4-12.6 nmol/min·mg |
mol wt【分子量】 | ~110 kDa |
NCBI accession no.【NCBI登记号】 | NM_014572 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −70℃ |
Gene Information | human ... LATS2(26524) |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 1 |