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Lesinurad

产品编号:4119808
规格:≥98% (HPLC)
CAS NO:878672-00-5
包装规格:10 MG,50 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
411980810 MG1220
411980850 MG4490
产品别名

878672-00-5

Lesinurad

RDEA 594

2-[[5-Bromo-4-(4-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic acid

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C17H14BrN3O2S
Molecular weight
404.28
MDL number
MFCD22572730
PubChem Substance ID【PubChem化学物质编号】
329825493
NACRES
NA.77
Biochem/physiol Actions【生化/生理作用】
Lesinurad is a selective inhibitor of Urate transporter 1 (URAT1), a urate-anion exchanger which is responsible for the majority of uric acid reabsorption from the renal tubular lumen. Lesinurad thus reduces serum uric acid levels. Lesinurad has been approved for use in combination with a xanthine oxidase inhibitor to treat hyperuricemia associated with gout.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
powder
color【颜色】
white to beige
solubility【溶解性】
DMSO: 25 mg/mL, clear
storage temp.【储存温度】
−20℃
SMILES string
BrC1=NN=C(SCC(O)=O)N1C2=C3C(C=CC=C3)=C(C4CC4)C=C2
InChI
1S/C17H14BrN3O2S/c18-16-19-20-17(24-9-15(22)23)21(16)14-8-7-11(10-5-6-10)12-3-1-2-4-13(12)14/h1-4,7-8,10H,5-6,9H2,(H,22,23)
InChI key
FGQFOYHRJSUHMR-UHFFFAOYSA-N
Gene Information
human ... SLC22A12(116085)
packaging【包装】
10, 50 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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