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LYS6K2
产品性质
Assay【测定】 | >95% (HPLC) |
form【形式】 | lyophilized powder |
mol wt【分子量】 | ~445.4 |
shipped in【运输】 | ambient |
storage temp.【储存温度】 | −20℃ |
基本信息
Biochem/physiol Actions【生化/生理作用】 | A selective inhibitor of the p70 ribosomal S6 kinase (S6K). Blocks the phosphorylation of S6 at concentrations as low as 0.1-0.3 uM with no activity at GSK3beta and Erk1/2 at 10 uM (2). Useful tool to dissect insulin receptor signaling pathways and was employed to show that the action of mTORC1 on SREB P-1c expression is not mediated by S6K. Cell permeable. |
Reconstitution【重悬】 | Formulated as a lyophilized powder. May be dissolved in DMSO (1 mg/mL) or DMF (3 mg/mL, warm). |
产品说明
Storage and Stability【储存及稳定性】 | Store desiccated as supplied at -20℃ for up to 3 years. Store solutions at -20℃ for up to 3 months. |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |