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MAL-dPEG®12-Tris(m-dPEG®24)3
产品别名
MAL-dPEG®12-Tris(m-dPEG®24)3
MAL-NH-PEG600-Tris(mPEG1000)3
Branched Maleimide-PEG-m
Branched mPEG-maleimide
MAL-PEG12-Tris(m-PEG24)3
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C194H378N6O94 |
| Molecular weight | 4299.06 |
| Features and Benefits【特点和优势】 | MAL-dPEG12-Tris(m-dPEG24)3 is a thiol-reactive, methyl-terminated, four-arm monodispersed PEG product designed to modulate biodistribution of conjugates. Tris forms the core of the molecule. Three equal-length methyl-terminated long arms plus one maleimido-terminated short arm extend from the tris core. From the maleimido olefin to the terminal methyl groups on each arm, the end-to-end length of this product is 127 atoms with an average distance of 103.7 Å. The amphiphilic PEG imparts hydrophilicity to conjugates, reduces or eliminates the conjugates′ antigenicity, and increases the hydrodynamic volume of conjugated molecules. Applications for this product include eradicating renal clearance, maintaining in vivo circulation for more extended periods, and suppressing immune responses to conjugates. |
| Legal Information【法律信息】 | Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681 dPEG is a registered trademark of Quanta BioDesign |
产品性质
| Assay【测定】 | >95% (HPLC) |
| form【形式】 | solid or viscous liquid |
| reaction suitability | reaction type: Pegylations |
| polymer architecture【聚合物结构设计】 | functionality: monofunctional |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | −20℃ |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
