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Microbial Transglutaminase
| 产品编号： | 4120251 |
| 规格： | lyophilized powder, ≥12 units/mg protein |
| 包装规格： | 25 units，250 units |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品性质
| form【形式】 | lyophilized powder |
| Quality Level【质量水平】 | 200 |
| Specific Activity | ≥12 units/mg protein |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
基本信息
| General description【一般描述】 | Transglutaminases (TG) are a family of enzymes that catalyze isopeptide bond formation. This bond formation occurs between the γ-carboxyamide group of glutamine and various primary amines (primarily the ε-amino group of lysine). The resulting intermolecular or intramolecular cross-linking of transglutaminase is highly stable and shows high resistance to proteolytic degradation. The transglutaminase crosslinking activity support the formation of blood clots , skin and hair. On the other hand, TG is now being implicated in Celiac disease as well as in Huntington and Parkinson diseases. Historically, Microbial transglutaminase has been heavily used in the food industry. Microbial TG is often preferred for newer applications (such as site-specific protein modification and antibody drug conjugation) due to its small molecular weight and lack of calcium dependency when compared to the mammalian forms. |
| Application【应用】 | Microbial Transglutaminase has been used for:
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| Features and Benefits【特点和优势】 |
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| Preparation Note【制备说明】 | For R&D use only. Not for drug, household, or other uses. Please consult the Safety Data Sheet for information regarding hazards and safe handling practices |
产品说明
| Storage and Stability【储存及稳定性】 | Store the freeze-dried product at –20 ℃. It is recommended to store the reconstituted protein in working aliquots at –20 ℃ to avoid repeated freeze/ thaw cycles. |
安全信息
| Pictograms【象形图】 | GHS08 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H334 |
| Precautionary Statements | P261 - P284 - P304 + P340 + P312 - P501 |
| Hazard Classifications【危险分类】 | Resp. Sens. 1 |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 1 |
