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Milli-Mark® Anti-CD23-FITC Antibody, clone MHM6
产品别名
Milli-Mark® Anti-CD23-FITC Antibody, clone MHM6
Low affinity immunoglobulin epsilon Fc receptor, Lymphocyte IgE receptor, Fc-epsilon-RII, BLAST-2, Immunoglobulin E-binding factor, C-type lectin domain family 4 member J
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.44 |
| General description【一般描述】 | CD23 is a 45 kDa type II membrane glycoprotein belonging to the C-type lectin family, and is identical to the low affinity IgE receptor (FceRII) (Kikutani, 1987; Aubry, 1987). CD23 is primarily expressed on B cells and monocytes including a strong expression on EBV-transformed B lymphoblasts (Sarfati, 1997; Sarfati, 1995). CD23 is also present on a large variety of other cells such as T cells, eosinophils, platelets, Langerhans cells, and a subset of thymic epithelial cells (Sarfati, 1995). However, CD23 is absent in a large number of normal non-lymphoid human tissues, such as, central nervous system, endocrine glands, gastrointestinal, respiratory, urinary, and female/male reproductive system, skin, bone, cartilage, connective tissue, muscles, peripheral nerves, vessels, mesothelium, synovium, placenta, and umbilical cord (Pallesen, 1987). Anti-CD23, MHM6, was included in the Second, Third, Fourth, and Fifth International Workshop and Conference on Human Leukocyte Differentiation Antigens, and studies by a number of laboratories confirmed its reactivity with CD23 (Sarfati, 1995). |
| Specificity【特异性】 | Antibody recognizes Human CD23 antigen. |
| Immunogen【免疫原】 | EBV-transformed B-lymphoblastoid cells |
| Application【应用】 | Detect CD23 using this Milli-Mark Anti-CD23-FITC Antibody, clone MHM6 validated for use in FC. Research Sub Category Immunoglobulins & Immunology Research Category Inflammation & Immunology |
| Quality【质量】 | Evaluated by flow cytometry using human lymphocytes. |
| Physical form【外形】 | Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2. Protein A purified |
| Analysis Note【分析说明】 | Control human lymphocytes |
| Legal Information【法律信息】 | MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | FITC conjugate |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | MHM6, monoclonal |
| species reactivity | human |
| manufacturer/tradename | Milli-Mark® |
| technique(s) | flow cytometry: suitable |
| isotype【同位素/亚型】 | IgG1κ |
| NCBI accession no.【NCBI登记号】 | NP_001993 |
| UniProt accession no.【UniProt登记号】 | P06734 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | 45 kDa (Kikutani, 1987; Aubry, 1987) |
| Storage and Stability【储存及稳定性】 | Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
