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Nelarabine
产品价格查看更多规格...
产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4139091 | 10 MG | 1710 | |||
4139091 | 50 MG | 6290 |
产品别名
121032-29-9
Nelarabine
Arranon
9-β-D-Arabinofuranosyl-6-methoxy-9H-purin-2-amine
506U78
Atriance
GW-506U78
506U
2-amino-9-β-D-arabinofuranosyl-6-methoxy-9H-purine
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C11H15N5O5 |
Molecular weight | 297.27 |
Biochem/physiol Actions【生化/生理作用】 | Nelarabine is an antineoplastic purine nucleoside analog used in T-cell acute lymphoblastic leukemia. It is a pro-drug of Ara-G, which is converted by cellular kinases to the active 5′-triphosphate, Ara-GTP. Incorporation of Ara-GTP into DNA leads to inhibition of DNA synthesis and apoptosis. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
storage condition【储存条件】 | desiccated |
color【颜色】 | white to beige |
solubility【溶解性】 | H2O: 5 mg/mL, clear (warmed) |
storage temp.【储存温度】 | 2-8℃ |
SMILES string | O[C@@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C=NC3=C2N=C(N)N=C3OC |
InChI | 1S/C11H15N5O5/c1-20-9-5-8(14-11(12)15-9)16(3-13-5)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2,12,14,15)/t4-,6-,7+,10?/m1/s1 |
InChI key | IXOXBSCIXZEQEQ-KBNQYOMWSA-N |
packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |