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Oxaphenamide
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4139437 | 100 MG | 1127 |
产品别名
526-18-1
Oxaphenamide
4′-Hydroxysalicylanilide
Osalmide
2-Hydroxy-N-(4-hydroxyphenyl)benzamide
p-hydroxyphenylsalicylamide
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C13H11NO3 |
Molecular weight | 229.23 |
EC number【EC 号】 | 208-385-9 |
MDL number | MFCD00020026 |
NACRES | NA.77 |
Biochem/physiol Actions【生化/生理作用】 | Osalmid is a potent inhibitor of ribonucleotide reductase small subunit M2 (RRM2) that potently inhibits HBV DNA and cccDNA synthesis in HepG2.2.15 cells. Osalmid inhibits RR (ribonucleotide reductase) activity in vivo, and exhibits synergistic effect with lamivudine on inactivation mutant HBV strain. Osalmid is a biliation activator (choleretic agent), but a mechanism of this activity remains unknown. |
产品性质
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
color【颜色】 | white to beige |
solubility【溶解性】 | DMSO: 2 mg/mL, clear |
storage temp.【储存温度】 | 2-8℃ |
InChI | 1S/C13H11NO3/c15-10-7-5-9(6-8-10)14-13(17)11-3-1-2-4-12(11)16/h1-8,15-16H,(H,14,17) |
InChI key | LGCMKPRGGJRYGM-UHFFFAOYSA-N |
安全信息
Pictograms【象形图】 | GHS07 |
Signal word【警示用语:】 | Warning |
Hazard Statements | H302 |
Precautionary Statements | P264 - P270 - P301 + P312 + P330 - P501 |
Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |