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Oxaphenamide

产品编号:4139437
规格:≥98% (HPLC)
CAS NO:526-18-1
包装规格:100 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
4139437100 MG1127
产品别名

526-18-1

Oxaphenamide

4′-Hydroxysalicylanilide

Osalmide

2-Hydroxy-N-(4-hydroxyphenyl)benzamide

p-hydroxyphenylsalicylamide

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C13H11NO3
Molecular weight
229.23
EC number【EC 号】
208-385-9
MDL number
MFCD00020026
NACRES
NA.77
Biochem/physiol Actions【生化/生理作用】
Osalmid is a potent inhibitor of ribonucleotide reductase small subunit M2 (RRM2) that potently inhibits HBV DNA and cccDNA synthesis in HepG2.2.15 cells. Osalmid inhibits RR (ribonucleotide reductase) activity in vivo, and exhibits synergistic effect with lamivudine on inactivation mutant HBV strain. Osalmid is a biliation activator (choleretic agent), but a mechanism of this activity remains unknown.
产品性质
Assay【测定】
≥98% (HPLC)
form【形式】
powder
color【颜色】
white to beige
solubility【溶解性】
DMSO: 2 mg/mL, clear
storage temp.【储存温度】
2-8℃
InChI
1S/C13H11NO3/c15-10-7-5-9(6-8-10)14-13(17)11-3-1-2-4-12(11)16/h1-8,15-16H,(H,14,17)
InChI key
LGCMKPRGGJRYGM-UHFFFAOYSA-N
安全信息
Pictograms【象形图】
GHS07
Signal word【警示用语:】
Warning
Hazard Statements
H302
Precautionary Statements
P264 - P270 - P301 + P312 + P330 - P501
Hazard Classifications【危险分类】
Acute Tox. 4 Oral
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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