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Procathepsin K from mouse
| 产品编号： | 4139960 |
| 规格： | recombinant, expressed in E. coli, ≥95% (SDS-PAGE) |
| 包装规格： | 10 μG，50 μG，1 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Procathepsin K from mouse
Cathepsin O
CTSO
CTSO2
Cathepsin O2
CTSK
Cathepsin X
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | Cathepsin K is a member of the papain cysteine proteinase family and has been identified as the predominant proteinase responsible for the resorption of the bone matrix. The enzyme cleaves proteins such as collagen type I, collagen type II and osteonectin and therefore plays a role in bone remodeling and resorption in diseases such as osteoporosis, osteolytic bone metastasis and rheumatoid arthritis (Bromme and Okamoto, 1995; Drake, F. et al 1996; Bossard et al, 1996). Cathepsin K is synthesized as an inactive proenzyme (35.1 kDa) that is converted to its mature active form (23.6 kDa) by proteolytic cleavage of its 99-amino-acid propeptide domain. The in-vitro processing of procathepsin K to mature cathepsin K is autocatalytic. |
| Physical form【外形】 | 2.5 mg/mL solution in 25 mM Na2HPO4 and 500 mM NaCl (pH 7.0). |
产品性质
| biological source【生物来源】 | mouse |
| recombinant【重组】 | expressed in E. coli |
| Assay【测定】 | ≥95% (SDS-PAGE) |
| form【形式】 | liquid |
| mol wt【分子量】 | 35.5 kDa |
| packaging【包装】 | pkg of 1 mg pkg of 10 μg pkg of 50 μg |
| concentration【浓度】 | 2.5 mg/mL |
| UniProt accession no.【UniProt登记号】 | P43235 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
| Gene Information | mouse ... CATK(1513) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
