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Safinamide Mesylate

产品编号:4140453
规格:Pharmaceutical Secondary Standard; Certified Reference Material
CAS NO:202825-46-5
包装规格:50 mg
产品类别:进口试剂
品牌:Supelco
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
414045350 mg5950
产品别名

202825-46-5

Safinamide Mesylate

Safinamide mesylate salt

(S)-(+)-2-[[4-(3-Fluorobenzoxy)benzyl]amino]propanamide; (S)-2-[[4-[(3-Fluorobenzyl)oxy]benzyl]amino]propanamide; FCE-26743; PNU-151774E, NW-1015;

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C17H19FN2O2 · xCH4O3S
Molecular weight
302.34 (free base basis)
MDL number
MFCD15145475
General description【一般描述】
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Biochem/physiol Actions【生化/生理作用】
Safinamide is a highly selective and reversible monoamine oxidase type B (MAO-B) inhibitor that increases neostriatal dopamine concentration. In addition, safinamide is voltage-dependent sodium and calcium channel blocker. It appears to bind to the batrachotoxin-sensitive site 2 of the voltage-sensitive sodium channels. Safinamide blocks N and L-type calcium channels and inhibits glutamate and aspartate release from synaptic terminals.
Analysis Note【分析说明】
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
Other Notes【其他说明】
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Footnote【附注】
To see an example of a Certificate of Analysis for this material enter LRAC4350 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
产品性质
grade【等级】
certified reference material
pharmaceutical secondary standard
form【形式】
powder
CofA
current certificate can be downloaded
packaging【包装】
pkg of 50 mg
storage temp.【储存温度】
2-8℃
SMILES string
CS(O)(=O)=O.C[C@H](NCc1ccc(OCc2cccc(F)c2)cc1)C(N)=O
InChI
1S/C17H19FN2O2.CH4O3S/c1-12(17(19)21)20-10-13-5-7-16(8-6-13)22-11-14-3-2-4-15(18)9-14;1-5(2,3)4/h2-9,12,20H,10-11H2,1H3,(H2,19,21);1H3,(H,2,3,4)/t12-;/m0./s1
InChI key
YKOCHIUQOBQIAC-YDALLXLXSA-N
Gene Information
human ... MAOB(4129)
安全信息
Pictograms【象形图】
GHS07,GHS08
Signal word【警示用语:】
Warning
Hazard Statements
H302 - H319 - H361d
Precautionary Statements
P202 - P264 - P270 - P301 + P312 - P305 + P351 + P338 - P308 + P313
Hazard Classifications【危险分类】
Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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