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产品性质
| recombinant【重组】 | expressed in E. coli |
| Assay【测定】 | 70-95% (SDS-PAGE) |
| form【形式】 | frozen liquid |
| mol wt【分子量】 | ~39 kDa |
| concentration【浓度】 | 0.2 μg/μL |
| accession no.【登记号】 | P10636-3 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
| Gene Information | human ... MAPT(4137) |
基本信息
| Application【应用】 | Useful for kinase assay and Western blot. |
| Biochem/physiol Actions【生化/生理作用】 | Recombinant full-length human tag-free Tau-316 was expressed in E. coli cells. Tau-316 encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. Tau-316 transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type (1). Tau-316 gene mutations have been associated with several neurodegenerative disorders such as Alzheimer′s disease, Pick′s disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy (2). |
| Sequence【序列】 | Full Length |
| Reconstitution【重悬】 | Formulated in 50mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM PMSF, with 25% glycerol. |
产品说明
| Storage and Stability【储存及稳定性】 | Store in aliquots at -70℃. Avoid freeze/thaw cycles. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
