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富马酸替诺福韦二吡呋酯
Tenofovir Disoproxil Fumarate
| 产品编号： | 4140907 |
| 规格： | Pharmaceutical Secondary Standard; Certified Reference Material |
| CAS NO： | 202138-50-9 |
| 包装规格： | 500 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Supelco |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4140907 | 500 MG | 3290 |
产品别名
202138-50-9
富马酸替诺福韦二吡呋酯
Tenofovir Disoproxil Fumarate
Bis{[(Isopropoxycarbonyl)oxy]methyl} ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate fumarate
Bis(POC)PMPA fumarate
替诺福韦酯 富马酸酯
双{[((异丙氧基羰基)氧基]甲基}({[((2R)-1-(6-氨基-9H-嘌呤-9-基)-2-丙烷基]氧基}甲基)膦酸酯 富马酸酯
Bis(POC)PMPA 富马酸酯
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C19H30N5O10P · C4H4O4 |
| Molecular weight | 635.51 |
| MDL number | MFCD08141829 |
| NACRES | NA.24 |
| General description【一般描述】 | Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards |
| Biochem/physiol Actions【生化/生理作用】 | 富马酸替诺福韦酯是替诺福韦的一种前药，一种可引起DNA转录提前终止的核苷酸类似物逆转录酶抑制剂(nRTI)。在T细胞系和原代血淋巴细胞中，替诺福韦酯的抗病毒活性是替诺福韦的100倍以上，原因就在于其快速的细胞间摄取。富马酸替诺福韦酯在HIV/AIDS和慢性乙肝病毒感染的预防和治疗中已被单独和经多种联合使用，并位于国际卫生组织的基本药品清单中。 |
| Analysis Note【分析说明】 | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
| Other Notes【其他说明】 | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Footnote【附注】 | To see an example of a Certificate of Analysis for this material enter LRAB2763 in the Documents slot below. This is an example certificate only and may not be the lot that you receive. |
产品性质
| Quality Level【质量水平】 | 300 |
| grade【等级】 | certified reference material pharmaceutical secondary standard |
| CofA | current certificate can be downloaded |
| packaging【包装】 | pkg of 500 mg |
| application(s) | pharmaceutical |
| format【格式】 | neat |
| pharmacopeia traceability【药典可追溯性】 | traceable to USP 1643656 |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | OC(/C=C/C(O)=O)=O.NC1=C2C(N(C[C@@H](C)OCP(OCOC(OC(C)C)=O)(OCOC(OC(C)C)=O)=O)C=N2)=NC=N1 |
| InChI | 1S/C19H30N5O10P.C4H4O4/c1-12(2)33-18(25)28-9-31-35(27,32-10-29-19(26)34-13(3)4)11-30-14(5)6-24-8-23-15-16(20)21-7-22-17(15)24;5-3(6)1-2-4(7)8/h7-8,12-14H,6,9-11H2,1-5H3,(H2,20,21,22);1-2H,(H,5,6)(H,7,8)/b;2-1+/t14-;/m1./s1 |
| InChI key | VCMJCVGFSROFHV-WZGZYPNHSA-N |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
