您的位置：首页 > 产品中心 > TFIIH, p62 subunit human
TFIIH, p62 subunit human
| 产品编号： | 4140978 |
| 规格： | recombinant, expressed in E. coli, ≥70% (SDS-PAGE) |
| 包装规格： | 10 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
TFIIH, p62 subunit human
BTF2
TFIIH
TFB1
基本信息
| NACRES | NA.26 |
| Biochem/physiol Actions【生化/生理作用】 | TFIIH, a multi-subunit complex is involved in several biological fundamental mechanisms of the cell: transcription, nucleotide excision repair and cell cycle regulation. p62 is one of the six subunits that constitutes the core of TFIIH. Analysis of the expression of the p62 gene reveals an over-expression in testis tissue. This subunit of TFIIH participates in a variety of protein-protein interactions. For example, Rb competes with TBP and p62 for binding to E2F thus repressing E2F-mediated trans-activation; herpes simplex virus VP16 and human p53 directly interact with the p62 subunit of TFIIH. In addition, TFIIH, via p62 phosphorylation is the major target for mitotic inactivation of transcription. |
| Physical form【外形】 | Clear and colorless frozen liquid solution |
| Preparation Note【制备说明】 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice. |
产品性质
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in E. coli |
| Assay【测定】 | ≥70% (SDS-PAGE) |
| form【形式】 | frozen liquid |
| mol wt【分子量】 | ~64.4 kDa |
| packaging【包装】 | pkg of 10 μg |
| storage condition【储存条件】 | avoid repeated freeze/thaw cycles |
| concentration【浓度】 | 750 μg/mL |
| color【颜色】 | clear colorless |
| NCBI accession no.【NCBI登记号】 | NM_005316 |
| UniProt accession no.【UniProt登记号】 | P32780 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
| Gene Information | human ... GTF2H1(2965) |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
