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Vildagliptin
产品价格查看更多规格...
产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4141369 | 50 MG | 712 | |||
4141369 | 250 MG | 3300 |
产品别名
274901-16-5
Vildagliptin
(S)-1-(((1R,3R,5R,7S)-3-hydroxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile
(2S)-1-[[(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-2-pyrrolidinecarbonitrile
LAF-237
NVP-LAF237
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C17H25N3O2 |
Molecular weight | 303.40 |
MDL number | MFCD08275142 |
Biochem/physiol Actions【生化/生理作用】 | Vildagliptin ia a selective inhibitor of dipeptidyl peptidase 4 (DPP4). This enzyme breaks down the incretins GLP-1 and GIP, gastrointestinal hormones that are released in response to a meal. By preventing GLP-1 and GIP inactivation, GLP-1 and GIP are able to potentiate the secretion of insulin and suppress the release of glucagon by the pancreas. |
产品性质
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
optical activity【旋光性】 | [α]/D -81 to -91°, c = 0.1 in methanol |
color【颜色】 | white to beige |
solubility【溶解性】 | DMSO: 2 mg/mL, clear |
storage temp.【储存温度】 | 2-8℃ |
SMILES string | N#C[C@H]1N(CCC1)C(CN[C@@](C[C@]2([H])C3)(C[C@@](C2)([H])C4)C[C@@]34O)=O |
InChI | 1S/C17H25N3O2/c18-9-14-2-1-3-20(14)15(21)10-19-16-5-12-4-13(6-16)8-17(22,7-12)11-16/h12-14,19,22H,1-8,10-11H2/t12-,13+,14-,16+,17-/m0/s1 |
InChI key | SYOKIDBDQMKNDQ-NHMCJKAESA-N |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |