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Vildagliptin

产品编号:4141369
规格:≥98% (HPLC)
CAS NO:274901-16-5
包装规格:50 MG,250 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
414136950 MG712
4141369250 MG3300
产品别名

274901-16-5

Vildagliptin

(S)-1-(((1R,3R,5R,7S)-3-hydroxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile

(2S)-1-[[(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-2-pyrrolidinecarbonitrile

LAF-237

NVP-LAF237

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C17H25N3O2
Molecular weight
303.40
MDL number
MFCD08275142
Biochem/physiol Actions【生化/生理作用】
Vildagliptin ia a selective inhibitor of dipeptidyl peptidase 4 (DPP4). This enzyme breaks down the incretins GLP-1 and GIP, gastrointestinal hormones that are released in response to a meal. By preventing GLP-1 and GIP inactivation, GLP-1 and GIP are able to potentiate the secretion of insulin and suppress the release of glucagon by the pancreas.
产品性质
Assay【测定】
≥98% (HPLC)
form【形式】
powder
optical activity【旋光性】
[α]/D -81 to -91°, c = 0.1 in methanol
color【颜色】
white to beige
solubility【溶解性】
DMSO: 2 mg/mL, clear
storage temp.【储存温度】
2-8℃
SMILES string
N#C[C@H]1N(CCC1)C(CN[C@@](C[C@]2([H])C3)(C[C@@](C2)([H])C4)C[C@@]34O)=O
InChI
1S/C17H25N3O2/c18-9-14-2-1-3-20(14)15(21)10-19-16-5-12-4-13(6-16)8-17(22,7-12)11-16/h12-14,19,22H,1-8,10-11H2/t12-,13+,14-,16+,17-/m0/s1
InChI key
SYOKIDBDQMKNDQ-NHMCJKAESA-N
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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