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VRK1, active, GST tagged human
产品编号: | 4141389 |
规格: | PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution |
包装规格: | 10 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
VRK1, active, GST tagged human
MGC117401
MGC138280
MGC142070
基本信息
NACRES | NA.32 |
General description【一般描述】 | VRK1 is a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. VRK1 is widely expressed in human tissues and actively dividing cells, such as those in testis, leukocytes, fetal liver and carcinomas. VRK1 regulate cell proliferation and phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN. The spinal muscular atrophy with pontocerebellar hypoplasia is caused by a mutation in the VRK1 gene. |
Physical form【外形】 | Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Preparation Note【制备说明】 | after opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles |
Legal Information【法律信息】 | PRECISIO is a registered trademark of sigma-aldrich Co. LLC |
产品性质
recombinant【重组】 | expressed in baculovirus infected Sf9 cells |
product line【产品线】 | PRECISIO® Kinase |
Assay【测定】 | ≥70% (SDS-PAGE) |
form【形式】 | buffered aqueous glycerol solution |
Specific Activity | 1.7-2.3 nmol/min·mg |
mol wt【分子量】 | ~71 kDa |
NCBI accession no.【NCBI登记号】 | NM_003384 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −70℃ |
Gene Information | human ... VRK1(7443) |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 1 |