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2-(Diphenylphosphanyl)benzamide
产品别名
343254-74-0
2-(Diphenylphosphanyl)benzamide
DPBM
Phosphine for Staundinger reduction
2-(Diphenylphosphino)-benzamide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C19H16NOP |
| Molecular weight | 305.31 |
| General description【一般描述】 | It is recommended to make fresh stock stolutions prior to each use. |
| Application【应用】 | 2-(Diphenylphosphanyl)benzamide (DPBM) is a phosphine useful in the Staudinger reduction in chemical biology and medicinal chemistry. Recently, DPBM was demonstrated to faciliate the reactivation of CRISPR/Cas9 functions by removing azidomethylnicotinyl (AMN) groups used to masked gRNA and inhibit CRISPR systems. AMN groups were originally added with the use of RNA probe NAI-N3 (cat# 913812). |
| Other Notes【其他说明】 | Conditional control of RNA-guided nucleic acid cleavage and gene editing Small-molecule control of protein function through Staudinger reduction A FRET-based ratiometric two-photon fluorescent probe for dual-channel imaging of nitroxyl in living cells and tissues |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% |
| form【形式】 | powder |
| storage temp.【储存温度】 | −20℃ |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
