您的位置：首页 > 产品中心 > 2429964-95-2， 4,6-Dimethyl-2-(methylsulfinyl)-3-nitropyridine
4,6-Dimethyl-2-(methylsulfinyl)-3-nitropyridine
产品别名
2429964-95-2
4,6-Dimethyl-2-(methylsulfinyl)-3-nitropyridine
SNAr probe
Cysteine-reactive electrophile
2-Sulfonylpyridine
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C8H10N2O3S |
| Molecular weight | 214.24 |
| Application【应用】 | 4,6-Dimethyl-2-(methylsulfinyl)-3-nitropyridine is a sulfoxide-containing fragment for covalent ligand discovery via cysteine labeling as demonstrated by Zamboldo and coworkers. Fragment electrophiles are useful in chemoproteomic and ligandability studies for both traditionally druggable proteins as well as ″undruggable,″ or difficult-to-target, proteins. Related useful products may include cysteine fragment KB02 (912131), IA alkyne (924237), IA 5-TAMRA (925020), desthiobiotin iodoacetamide (923826), or biotin iodoacetamide (B2059). |
| Other Notes【其他说明】 | 2-Sulfonylpyridines as Tunable, Cysteine-Reactive Electrophiles |
产品性质
| reaction suitability | reagent type: chemical modification reagent |
| Quality Level【质量水平】 | 100 |
| storage temp.【储存温度】 | 2-8℃ |
