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Anti-BRCA1 (Ab-2) Mouse mAb (MS13)
产品别名
Anti-BRCA1 (Ab-2) Mouse mAb (MS13)
Anti-Breast Cancer Susceptibility Protein
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | MS13, monoclonal |
| form【形式】 | liquid |
| contains【包含】 | ≤0.1% sodium azide as preservative |
| species reactivity | human |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | do not freeze |
| isotype【同位素/亚型】 | IgG1 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | 2-8℃ |
| packaging【包装】 | 100 μg in Plastic ampoule Please refer to vial label for lot-specific concentration. |
基本信息
| General description【一般描述】 | Purified mouse monoclonal antibody generated by immunizing mice with the specified iummunogen and fusing splenocytes with NS1 mouse myeloma cells. Recognizes the ~220 kDa BRCA1 protein. Anti-BRCA1 (Ab-2), mouse monoclonal, clone MS13, recognizes ~220 kDa BRCA1 in MCF-7 cells. It is validated for Western blotting, immunofluorescence, immunoprecipitation, and for paraffin sections. Recognizes the ~220 kDa BRCA1 protein in MCF-7 cells. Does not react with blood group antigens or growth factor receptors such as EGFR. Sold under license of U.S. Patent 5,753,441 and 6,162,897. |
| Immunogen【免疫原】 | recombinant, human BRCA1 Epitope: within amino acids 1-304 Human |
| Application【应用】 | Immunoblotting (2 µg/ml, chemiluminescence; see application references) Immunofluorescence (see application references) Immunoprecipitation (see application references) Paraffin Sections (see application references) |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Physical form【外形】 | In 0.05 M sodium phosphate buffer, 0.2% gelatin. |
| Analysis Note【分析说明】 | Positive Control MCF7 cells |
| Other Notes【其他说明】 | Scully, R., et al. 1996. Science272, 123. Gudas, J.M., et al. 1996. Cell Growth Differ.7, 717. Vaughn, J.P., et al. 1996. Cell Growth Differ.7, 711. Goldgar, D.E. and Reilly, P.R. 1995. Nat. Genet.11, 113. Merajver, S.D., et al. 1995. Clin. Can. Res.1, 539. Merajver, S.D., et al. 1995. Nat. Genet.9, 439. Struewing, J.P., et al. 1995. Nat. Genet.11, 198. Thompson, M.E., et al. 1995. Nat. Genet.9, 444. Futreal, P.A., et al. 1994. Science266, 120. Miki, Y., et al. 1994. Science266, 66. Antibody should be titrated for optimal results in individual systems. |
| Legal Information【法律信息】 | Sold under license of U.S. Patents 5,753,441 and 6,162,897. CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
