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[CpRu(Fmoc-tyrosin)]CF3CO2
产品别名
[CpRu(Fmoc-tyrosin)]CF3CO2
[18F]Fluorophenylalanine peptide residue precursor
Fmoc-protected ruthenium tyrosine amino acid derivative
Peptide radiolabel precursor
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C31H26F3NO7Ru |
| Molecular weight | 682.61 |
| NACRES | NA.26 |
| Application【应用】 | The Ritter lab has developed a new method for direct labeling of polypeptides with the [18F]fluoride radiolabel. This Fmoc-protected ruthenium tyrosine is first incorporated into peptides, which is amenable to standard solid-phase peptide synthesis (SPPS) and is tolerant of all 20 canonical amino acids. Subsequent replacement of a single hydrogen with fluorine-18, with only minimal perturbation of the peptide structure, results in a site-specific, radiolabeled peptide tracer for use with positron emission tomography (PET) imaging in the study of various biological applications. |
| Caution【注意】 | Research quantities limited to 10 g. |
| Other Notes【其他说明】 | Site-SpecificDeoxyfluorination of Small Peptides with [18F]Fluoride |
| Legal Information【法律信息】 | Patent Application EP18204755.5 This product is manufactured pursuant to a license with Studiengesellschaft Kohle mbH |
产品性质
| form【形式】 | powder |
| reaction suitability | reaction type: Fmoc solid-phase peptide synthesis |
| mp | >300 ℃ |
| application(s) | peptide synthesis |
| functional group【官能团】 | Fmoc |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | O[C]1[CH][CH][C](CC(NC(OCC2C(C=CC=C3)=C3C4=C2C=CC=C4)=O)C(O)=O)[CH][CH]1.F[C-](F)F.O=C=O.[Ru+].c5cccc5 |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
