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Isoproterenol, Hydrochloride-CAS 51-30-9-Calbiochem

产品编号:4145249
规格:Phenethylamine derivative.
CAS NO:51-30-9
包装规格:100 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
4145249100 MG778
产品别名

51-30-9

Isoproterenol, Hydrochloride-CAS 51-30-9-Calbiochem

基本信息
Empirical Formula【经验(实验)分子式】
C11H17NO3 · xHCl
Molecular weight
211.26 (free base basis)
MDL number
MFCD00012603
General description【一般描述】
Phenethylamine derivative. Selective β-adrenergic agonist that increases cytosolic cAMP. Promotes glycogen breakdown and causes bronchodilation. Increases Cl- diffusion and potential difference in rabbit trachea cells through nitric oxide generation.
Phenethylamine derivative. Selective β-adrenergic agonist that stimulates adenylate cyclase activity. Promotes glycogen breakdown and causes bronchodilation. Increases Cl diffusion and potential difference in rabbit trachea cells through nitric oxide generation. Reported to activate MAP Kinase (ERK) by a Rap1 and B-Raf dependent process.
Biochem/physiol Actions【生化/生理作用】
Primary Target
β-adrenergic agonist
Product does not compete with ATP.
Reversible: no
Cell permeable: no
Warning【警告】
Toxicity: Irritant (B)
Reconstitution【重悬】
Unstable in solution; reconstitute just prior to use.
Other Notes【其他说明】
Schmitt, J.M., and Stork, P.J. 2000. J. Biol. Chem.275, 25342.
Carmena, M.J., et al. 1997. Prostate 33, 46.
Takemura, H., et al. 1995. J. Pharmacol. Exp. Ther. 274, 584.
Kishimoto, I., et al. 1994. J. Biol. Chem.269, 28300.
Macaulay, S.L., et al. 1994. Mol. Cell Biochem.141, 27.
Yashiro, K., et al. 1994. J. Biochem.115, 1040.
Ladenheim, R.G., et al. 1993. J. Neurochem.60, 260.
von Zastrow, M., et al. 1993. J. Biol. Chem.268, 763.
Mokhtari, A., et al. 1985. J. Cyclic Nucleotide Protein Phosphorylation Res.10, 213.
Legal Information【法律信息】
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥99% (TLC)
form【形式】
solid
manufacturer/tradename
Calbiochem®
storage condition【储存条件】
OK to freeze
protect from light
color【颜色】
white to off-white
white
solubility【溶解性】
ethanol: soluble
water: soluble
shipped in【运输】
ambient
storage temp.【储存温度】
10-30℃
InChI
1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H
InChI key
IROWCYIEJAOFOW-UHFFFAOYSA-N
packaging【包装】
100 mg in Plastic ampoule
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 2
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