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N-Hydroxysuccinimide ester-poly(ethylene glycol)-b-poly(ε-caprolactone)
| 产品编号： | 4145774 |
| 规格： | PEG average Mn 5,000, PCL average Mn 5,000 |
| 包装规格： | 500 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
N-Hydroxysuccinimide ester-poly(ethylene glycol)-b-poly(ε-caprolactone)
PEG-PCL
NHS ester-PEG-PCL
PEG-b-PCL
NHS ester PEG-PCL diblock copolymer
结构式
基本信息
| Linear Formula【线性分子式】 | C10H14NO5S[C2H4O]n[C6H10O2]mH |
| Application【应用】 | N-Hydroxysuccinimide ester-poly(ethylene glycol)-b-poly(ε-caprolactone) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PCL block. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). Additionally, well-defined nanoparticles with tunable size and properties can be prepared by altering the molecular weight ratios between hydrophilic and hydrophobic blocks, as well as by controlling formulation parameters. The NHS ester functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery. |
产品性质
| form【形式】 | powder or solid |
| mol wt【分子量】 | PCL average Mn 5,000 PEG average Mn 5,000 |
| color【颜色】 | white to off-white |
| PDI | ≤1.3 (by GPC) |
| storage temp.【储存温度】 | −20℃ |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
