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TrueGel3D Crosslinker
产品性质
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
基本信息
| General description【一般描述】 | CD cell-degradable crosslinker is comprised of conjugated peptide along with polyethylene glycol and thiol (SH) groups. The thiol groups form stable thioether bond with thiol-reactive groups of the polymers (Mal-PVA, Mal-Dextran, SG-PVA and SG-Dextran) and results in a stable hydrogel. The conjugated peptide has matrix metalloprotease (MMP)-cleavage sites (Pro-Leu-Gly-Leu-Trp-Ala), which allows matrix metalloproteases (MMP1, MMP3, MMP7 and MMP9) to locally degrade the polymer network. It allows cells to spread and migrate within the gel if they express the indicated MMPs. |
| Application【应用】 | TRUECD is used to crosslink PVA and dextran polymers to generate cell-degradable hydrogel |
| Features and Benefits【特点和优势】 | MMP degradable |
| Components【组分】 | TRUECD contains CD cell-degradable crosslinker lyophilized and water. |
| Caution【注意】 | Avoid prolong exposure of CD cell-degradable crosslinker to air |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
