Anti-G_qα- and G₁₁α-Subunits, Internal (283-300) Rabbit pAb

rabbit

100

purified antibody

primary antibodies

polyclonal

liquid

preservative

mouse, rat, human

Calbiochem^®

OK to freeze
avoid repeated freeze/thaw cycles

IgG

wet ice

−70℃

50 μL in Plastic ampoule

Anti-G_qα- and G₁₁α-Subunits, Internal (283-300), rabbit polyclonal, recognizes the ~42 kDa G_qα- and the ~43 kDa G₁₁α-subunits. Validated for use in WB and neutralization studies.
Protein A purified rabbit polyclonal antibody. Recognizes the ~42 kDa G_qα- and the ~43 kDa G₁₁α-subunit proteins.
Recognizes the ~42 kDa G_qα- and the ~43 kDa G₁₁α-subunits. Does not cross-react with other G-proteins of the non-pertussis toxin-sensitive family.

a synthetic peptide (IMYSHLVDYFPEYDGPQR) corresponding to an internal amino acid sequence shared by human, mouse, and rat G_qα- and G₁₁α-subunits

Immunoblotting (1:1000)

Neutralization Studies (see comments)

Toxicity: Standard Handling (A)

The antibody recognizes both G_qα and G₁₁α since they both share the internal sequence represented by the immunizing peptide. The antibody may also be useful to block receptor G protein coupling. Does not cross-react with other G proteins of the non-pertussis toxin sensitive family. Variables associated with assay conditions will dictate the proper working dilution.
Wange, R.L., et al. 1991. J. Biol. Chem. 266, 11409.
Pang, I-H., and Sternweis, P.C. 1990. J. Biol. Chem. 265, 18707.
Strathmann, M., et al. 1989. Proc. Natl. Acad. Sci. USA86, 7407.

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