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Adenosine Deaminase Inhibitor, DCF-CAS 53910-25-1-Calbiochem
产品编号: | 4153572 |
规格: | The Adenosine Deaminase Inhibitor, DCF, also referenced under CAS 53910-25-1, controls the biological activity of Adenosine Deaminase. |
CAS NO: | 53910-25-1 |
包装规格: | 10 MG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品价格查看更多规格...
产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4153572 | 10 MG | 2380 |
产品别名
53910-25-1
Adenosine Deaminase Inhibitor, DCF-CAS 53910-25-1-Calbiochem
2'-Deoxycoformycin, (8R)-3-(2-deoxy-β-D-erythro- pentofuranosyl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol, Pentostatin, S. antibioticus
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C11H16N4O4 |
Molecular weight | 268.27 |
General description【一般描述】 | A cell-permeable purine nucleoside compound that acts as a highly potent, tight binding transition state analog inhibitor of adenosine deaminase (ADA; Ki= 2.5 pM against partially purified human erythrocytes, and 0.48 to 9.1 nM against rat liver, rat intestine, rat hepatoma and human B cells). Reported to be an immunomodulator and exert selective toxicity towards lymphocytes. |
Warning【警告】 | Toxicity: Harmful & Carcinogenic / Teratogenic (E) |
Reconstitution【重悬】 | Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. |
Other Notes【其他说明】 | Robak, T. 2007. Cancer Treat. Rev.33, 710. Klohs, W.D. and Kraker, A.J., 1992. Pharmacol. Rev.44, 459. Agarwal, R.P., et al. 1977. Biochem. Pharmacol.26, 359. Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges. |
Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | solid |
manufacturer/tradename | Calbiochem® |
storage condition【储存条件】 | OK to freeze protect from light |
color【颜色】 | white |
solubility【溶解性】 | DMSO: 10 mg/mL, clear, colorless water: 50 mg/mL, clear, colorless |
shipped in【运输】 | ambient |
storage temp.【储存温度】 | 2-8℃ |
SMILES string | O[C@@H]1CNC=NC2=C1N=CN2[C@@H]3O[C@H](CO)[C@H](O)C3[H] |
InChI | 1S/C11H16N4O4/c16-3-8-6(17)1-9(19-8)15-5-14-10-7(18)2-12-4-13-11(10)15/h4-9,16-18H,1-3H2,(H,12,13)/t6-,7+,8+,9+/m0/s1 |
InChI key | FPVKHBSQESCIEP-JQCXWYLXSA-N |
packaging【包装】 | 10 mg in Glass bottle Packaged under inert gas |
安全信息
Pictograms【象形图】 | GHS06 |
Signal word【警示用语:】 | Danger |
Hazard Statements | H301 |
Precautionary Statements | P264 - P270 - P301 + P310 - P405 - P501 |
Hazard Classifications【危险分类】 | Acute Tox. 3 Oral |
Storage Class Code【储存分类代码】 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
WGK | WGK 3 |